Lehrstuhl für Pharmazeutische Biologie

    Publikationen Prof. Dr. Dr. M.J. Müller

    2017

    Cheng C, Balasubramanian S, Fekete A, Krischke M, Mueller MJ, Hentschel U, Oelschlaeger TA, Abdelmohsen UR (2017) Inhibitory potential of strepthonium A against Shiga toxin production in enterohemorrhagic Escherichia coli (EHEC) strain EDL933.
    Nat. Prod. Res. In press

    Oenel, A, Fekete, A, Krischke, M, Faul, SC, Gresser, G, Havaux, M, Mueller, MJ, Berger, S (2017) Enzymatic and non-enzymatic mechanisms contribute to lipid oxidation during seed aging.
    Plant Cell Physiol
    . In press

    Fuchs B, Breuer T, Findling S, Krischke M, Mueller MJ, Holzschuh A, Krauss J. (2017) Enhanced aphid abundance in spring desynchronizes predator-prey and plant-microorganism interactions.
    Oecologia 183, 469-478.


    2016

    Blättner S, Das S, Paprotka K, Eilers U, Krischke M, Kretschmer D, Remmele CW, Dittrich M, Müller T, Schuelein-Voelk C, Hertlein T, Mueller MJ, Huettel B, Reinhardt R, Ohlsen K, Rudel T, Fraunholz MJ. (2016) Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes.
    PLoS Pathog
    . 12:e1005857.

    Segerer G, Hadamek K, Zundler M, Fekete A, Seifried A, Mueller MJ, Koentgen F, Gessler M, Jeanclos E, Gohla A. (2016) An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.
    Sci Rep. 6, 35160.

    Muench M, Hsin CH, Ferber E, Berger S, Mueller MJ. (2016) Reactive electrophilic oxylipins trigger a heat stress-like response through HSFA1 transcription factors.
    J. Exp. Bot. 67, 6139-6148.

    Cerveau, D., Kraut, A., Stotz, H.U., Mueller, M.J., Coute, Y., Rey, P. (2016) Characterization of the Arabidopsis thaliana 2-Cys peroxiredoxin interactome.
    Plant Sci.
    252, 30-41.

    Walper E, Weiste C, Mueller MJ, Hamberg M, Dröge-Laser W. (2016) Screen Identifying Arabidopsis Transcription Factors Involved in the Response to 9-Lipoxygenase-Derived Oxylipins.
    PLoS One
    11(4):e0153216.

    Ruemer S, Krischke M, Fekete A, Lesch M, Mueller MJ, Kaiser WM. (2016) Methods to Detect Nitric Oxide in Plants: Are DAFs Really Measuring NO?
    Methods Mol Biol
    . 1424, 57-68.

    2015

    Hartmann L, Pedrotti L, Weiste C, Fekete A, Schierstaedt J, Göttler J, Kempa S, Krischke M, Dietrich K, Mueller MJ, Vicente-Carbajosa J, Hanson J, Dröge-Laser W. (2015) Crosstalk between two bZIP signaling pathways orchestrates salt-induced metabolic reprogramming in Arabidopsis roots.
    Plant Cell
    27, 2244-2260.

    Mueller SP, Krause DM, Mueller MJ, Fekete A. (2015) Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation.
    J. Exp. Bot.
    66, 4517-4526.

    Mülek M, Fekete A, Wiest J, Holzgrabe U, Mueller MJ, Högger P. (2015) Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach.
    J. Pharm. Biomed. Anal. 114, 71-81.

    Awad, J., Stotz, H.U., Fekete, A., Krischke, M., Engert, C., Havaux, M., Berger, S., Mueller, M.J.  (2015) 2-Cys peroxiredoxins and thylakoid peroxidase create a water-water cycle that is essential to protect the photosynthetic apparatus under high light stress conditions.
    Plant Physiol.
    167, 1592-1603.

    Ahmed, Z., Mayr, M., Zeeshan, S., Dandekar, T., Mueller, M.J., Fekete, A. (2015) Lipid-Pro: a computational lipid identification solution for untargeted lipidomics on data-independent acquisition tandem mass spectrometry platforms.
    Bioinformatics
    31(7), 1150-1153.


    2014

    Stotz, H.U., Findling, S., Nukarinen, E., Weckwerth, W., Mueller, M.J., Berger, S. (2014) A tandem affinity purification tag of TGA2 for isolation of interacting proteins in Arabidopsis thaliana.
    Plant Signal. Behavior 9(10):e972794.

    Scholl C, Wang Y, Krischke M, Mueller MJ, Amdam GV, Rössler W. (2014) Light exposure leads to reorganization of microglomeruli in the mushroom bodies and influences juvenile hormone levels in the honeybee.
    Dev Neurobiol.
    74, 1141-1153.

    Alsharafa, K., Vogel, M.O., Oelze, M.L., Moore, M., Stingl, N., König, K., Friedman, H., Mueller, M.J., Dietz, K.J. (2014) Kinetics of retrograde signalling initiation in the high light response of Arabidopsis thaliana.
    Philos Trans R Soc Lond B Biol Sci. 369(1640), 20130424. doi: 10.1098/rstb.2013.0424.


    Klinkenberg, J., Faist, H., Saupe, S., Lambertz, S., Krischke, M., Stingl, N., Fekete, A., Mueller, M.J., Feussner, I., Hedrich, R., Deeken, R. (2014) Two Fatty Acid Desaturases, STEAROYL-ACYL CARRIER PROTEIN Δ9-DESATURASE6 and FATTY ACID DESATURASE3, Are Involved in Drought and Hypoxia Stress Signaling in Arabidopsis Crown Galls.
    Plant Physiol.
    164, 570-583.


    2013

    Fuchs, B., Krischke, M., Mueller, M.J., Krauss, J. (2013) Peramine and olotrem B from endophyte-grass associations cascade up the food chain.
    J. Chem. Ecol. 39, 1385-1389.

    Schiebel, J., Kapilashrami, K., Fekete, A., Bommineni, G.R., Schaefer, C.M., Mueller, M.J., Tonge, P.J., Kisker, C. (2013) Structural basis for the recognition of mycolic acid precursors by KasA, a condensing enzyme and drug target from Mycobacterium tuberculosis.
    J. Biol. Chem. 288, 34190-34204.

    Boca, S., Koestler, F., Ksas, B., Chevalier, A., Leymarie, J., Fekete, A., Mueller, M.J., Havaux, M. (2013) Arabidopsis lipocalins AtCHL and AtTIL have distinct but overlapping functions for lipid protection and seed longevity.
    Plant Cell Environ. 37, 368-381.

    Pedrotti, L., Mueller, M.J., Waller, F. (2013) Piriformospora indica root colonization triggers local and systemic root responses and inhibits secondary colonization of distal roots.
    PLloS One (8(7):e69352.doi: 10.1371/journal.pone.0069352.

    Ramel, F., Ksas, B., Akkari, E., Mialoundama, A.S., Monnet, F., Krieger-Liszkay, A., Ravanat, J-L., Mueller, M.J., Bouvier, F., Havaux, M. (2013) ight-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen.
    Plant Cell 25, 1445-1462.

    Farmer, E.E., Mueller, M.J. (2013) ROS-mediated lipid peroxidation and RES-activated signalling.
    Ann. Rev. Plant Biology 64, 22.1-22.22.

    Grebner, W., Stingl, N.E., Oenel, A., Mueller, M.J., Berger, S. (2013) Lipoxygenase 6 - dependent oxylipin synthesis in roots is required for abiotic and biotic stress resistance of Arabidopsis thaliana.
    Plant Physiol. 161, 2159-2170.

    Stotz, H.U., Mueller, S., Zoeller, M., Mueller, M.J., Berger, S. (2013) TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins.
    J. Exp. Bot. 64, 963-974.

    Leikam, C., Hufnagel, A., Walz, S., Kneitz, S., Fekete, A., Müller, M.J., Eilers, M., Schartl, M., Meierjohann, S. (2013) Cystathionase mediates senescence evasion in melanocytes and melanoma cells.
    Oncogene 33, 771-782.

    Stingl, N., Krischke, M., Fekete, A., Mueller, M.J. (2013) Analysis of defense signals in Arabidopsis thaliana leaves by ultra performance liquid chromatography/ tandem mass spectrometry: jasmonates, salicylic acid, abscisic acid.
    Methods Mol. Biol. 1009, 103-113.

    2012

    Zoeller, M., Stingl, N., Krischke, M., Fekete, A., Waller, F., Berger, S., Mueller, M.J. (2012) Mechanisms and targets of lipid oxidation in the incompatible Pseudomonas-Arabidopsis interaction: Biogenesis of azelaic and pimelic acid.
    Plant Physiol. 160, 365-78.

    Rümer S, Krischke M, Fekete A, Mueller MJ, Kaiser WM. (2012) DAF-fluorescence without NO: Elicitor treated tobacco cells produce fluorescing DAF-derivatives not related to DAF-2 triazol.
    Nitric Oxide 27, 123-135.

    Kupke, J., Spaethe, J., Mueller, M.J., Rössler, W., Albert S. (2012) Molecular and biochemical characterization of the major royal jelly protein in bumblebees suggest a non-nutritive function.
    Insect. Biochem. Mol. Biol
    . 42, 647-654.

    Ott, C., Ross, K., Straub, S., Thiede, B., Götz, M., Goosmann, C., Krischke, M., Mueller, M.J., Krohne, G., Rudel, T., Kozjak-Pavlovic, V. (2012) Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes.
    Mol. Cell. Biol.
    32, 1173-1188.

    2011

    Albert, S., Gätschenberger, H., Azzami, K., Gimple, O., Grimmer, O., Sumner, S., Fujiyuki, T., Tautz, J., Mueller, M.J. (2011) Evidence of a novel immune response protein in the Hymenoptera.
    Insect Biochem. Mol. Biol. 41, 968-981.

    Stotz, H.U., Jikumaru, Y., Shimada, Y., Y., Sasaki, E., Stingl, N., Mueller, M.J., Kamiya, Y. (2011) Jasmonate-dependent and COI1-independent defense responses against sclerotinia sclerotium in Arabidopsis thaliana: Auxin is part of COI1-independent defense signalling.
    Plant Cell Physiol.
    52, 1941-1956.

    Peer, M., Bach, M., Mueller, M.J., Waller, F. (2011 Free sphingobases induce RBDOHD-dependent reactive oxygen species production in Arabidopsis thaliana leaves.
    FEBS Lett. 585, 3006-3010.

    Birtic, S., Ksas, B., Genty, B., Mueller, M.J., Triantaphylidès, C., Havaux, M. (2011) Using spontaneous photon emission to image lipid oxidation patterns in plant tissues.
    Plant J. 67, 1103-1115.http://www.ncbi.nlm.nih.gov/pubmed/21595761

    Sogabe, Y., Nakamura, H., Nagakawa, T., Hasegawa, S., Asano, T., Ohta, H., Yamaguchi, K., Mueller, M.J., Kodama, H., Nishiuchi, T. (2011) Visualization of Wounding-induced Root-to-Shoot Communication in Arabidopsis.
    Plant Signal Behav., 6, 1057-1039.

    Hasegawa, S., Sogabe, Y., Asanao, T., Nakagawa, T., Nakamura, H., Kodama, H., Ohta, H., Yamaguchi, K., Mueller, M.J., Nishiuchi, T. (2011) Gene expression analysis of wounding-induced root-to-shoot communication in Arabidopsis thaliana.
    Plant Cell Environ., 34, 705-716.

     

    2010

     

    Peer, M., Stegmann, M., Mueller, M.J., Waller, F. (2010) Pseudomonas syringae infection triggers de novo synthesis of phytosphingosine from sphinganine in Arabidopsis thaliana.
    FEBS Lett., 584, 4053-4056.

    Ellinger, S., Stingl, N.E., Kubigsteltig, I.I., Bals, T., Juenger, M., Pollmann, S., Berger, S., Schünemann, D., Mueller, M.J. (2010) DGL and DAD1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation.
    Plant Physiol. 153, 114-127.

    Seltmann, M.A., Stingl, N.E., Lautenschlaeger, J.,K., Krischke, M., Mueller, M.J., Berger, S. (2010) Differential impact of lipoxygenase 2 and jasmonates on natural and stress-induced senescence in  Arabidopsis thaliana.
    Plant Physiol., 152, 1940-1950.

    Bruinsma, M., van Broekhoven, S., Poelman, E.H., Posthumus, M.A., Mueller, M.J., van Loon, J.J., Dicke, M. (2010) Inhibition of lipoxygenase affects induction of both direct and indirect plant defences against herbivorous insects.
    Oecologia 162, 293-404.

    Gilles, S., Jacoby, D., Blume, C., Mueller, M.J., Jakob, T., Behrendt, H., Schaekel, K., Traidl-Hoffmann, C. (2010) Pollen-derived low-molecular weight factors inhibit 6-sulfo LacNAc1 dendritic cells' capacity to induce T-helper type 1 responses.
    Clin. Exp. All. 40, 269-278.

    Mueller, M.J. (2010) Isoprostane nomenclature: inherent problems may cause setbacks for the development of the isoprostanoid field.
    Prostaglandins Leukot. Essent. Fatty Acids 82, 71-81.



    2009

    Gilles, S., Mariani, V., Bryce., M., Mueller, M.J., Ring, J., Behrendt, H., Jakob, T., Traidl-Hoffmann, C. (2009) Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immue systems towards a Th2-dominated response.
    Allergy, Asthma & Clin. Immun. 5, 3.

    Durand, T., Bultel-Poncé, V., Guy, A., Berger, S., Mueller, M.J., Galano, J.-M. (2009) New Bioactive Oxylipins Formed by Non-enzymatic Free-Radical-Catalyzed Pathways: The Phytoprostanes.
    Lipids 44, 875-878.

    Mueller, M.J. (2009) Reactive electrophilic oxylipins: Pattern recognition and signaling.
    Phytochemistry 70, 1511-1521.

    Barden, A.E., Croft, K.D., Durand, T., Guy, A., Mueller, M.J., Mori, T.A. (2009) Flaxseed oil supplementation increases F1-phytoprostanes in healthy men.
    J. Nutrition 139, 1890-1895.

    Gilles, S., Mariani, V., Bryce, M., Mueller, M.J., Ring, J., Jakob, T., Pastore, S., Behrendt, H., Traidl-Hoffmann, C. (2009) Pollen derived E1-phytoprostanes signal via PPARg and NF-kB dependent mechanisms.
    J. Immunol. 182, 6653-6658.

    Bruinsma, M., Posthumus, M.A., Mumm, R., Mueller, M.J., van Loon, J.J.A., Dicke, M. (2009) Jasmonic acid-induced volatiles of Brassica oleracea attract parasitoid: effects of time, dose and comparison with induction by herbivores.
    J. Exp. Bot.
    60, 2575-2587.
    Comment: Wasternack, C., Hause, B. (2009) Emerging complexity: jasmonate induced volatiles affect paraitoid choice.
    J. Exp. Bot. 60, 2451-2453.

    Yarali, A., Krischke, M., Michels, B., Saumweber, T., Mueller, M.J., Gerber, B. (2009)
    Genetic distortion of the balance between punishment and relief learning in Drosophila.,
    J. Neurogenet.
    23, 235-247.


    2008

    Dueckershoff, K., Mueller, S., Mueller, M.J., Reinders, J. (2008) Impact of cyclopentenone-oxylipins on the proteome of Arabidopsis thaliana.
    Biochim. Biophys. Acta (Proteins and Proteomics) 1784, 1975-1985.

    Triantaphylides, C., Krischke, M., Hoeberichts, F.A., Ksas, B., Gresser, G., Havaux, M., Van Breusegem, F., Mueller, M.J. (2008) Singlet oxygen is the major reactive oxygen species involved in photo-oxidative damage to plants.
    Plant Physiol. 148, 960-968.

    Randolt K., Gimple, O., Geißendörfer, J., Reinders, J., Prusko, C., Mueller, M.J., Albert, S., Tautz, J., Beier, H. (2008) Immune-related proteins induced in the hemolymph after aseptic and septic injury differs in honey bee worker larvae and adults.
    Arch. Insect Biochem. Physiol. 69, 155-167.

    Mueller, S., Hilbert, B., Dueckershoff, K., Roitsch, T., Krischke, M., Mueller, M.J., Berger, S. (2008) General detoxification and stress responses are mediated by oxidized lipids through TGA transcription factors in Arabidopsis.
    Plant Cell 20, 768-785.
    Comment: Eckhardt, N.A. (2008) Oxylipin signaling in plant stress responses.
    Plant Cell 20, 495-497.


    2007

    Feldhaar, H., Straka, J., Krischke, M., Berthold, K., Stoll, S., Mueller, M.J., Gross, R. (2007) Nutritional upgrading for omnivor carpenter ants by the endosymbiont Blochmania.
    BMC Biology 5, 48.

    Efetova, M., Zeier, J., Riederer, M., Lee, C.W., Stingl, N., Mueller, M.J., Hartung, W, Hedrich, R., Deeken, R.  (2007) A central role of ABA in drought stress protection of Agrobacterium-induced  tumors on Arabidopsis,
    Plant Physiol. 145, 853-862.

    Schoenleben, S., Sickmann, A., Mueller, M.J., Reinders, J. (2007) Proteome analysis of Apis mellifera royal jelly.
    Anal. Bioanal. Chem. 389, 1087-1093.

    Arts, M.J., Grun, C., de Jong, R.L., Voss, H.-P., Bast, A., Mueller, M.J., Haenen, G.R. (2007) Oxidative degradation of lipids during mashing.
    J. Agric. Food Chem. 22, 7010-7014.

    Mariani, V., Gilles, S., Jakob, T., Thiel, M., Mueller, M.J., Ring, J., Behrendt, H., Traidl-Hoffmann, C. (2007) Immunomodulatory mediators from pollen enhance the migratory capacity of dendritic cells and licence them for Th2 attraction.
    J. Immunol. 178, 7623-7631.

    Gutermuth, J., Bewersdorff, M., Traidl-Hoffmann, C., Ring J., Mueller, M.J., Behrendt, H., Jakob, T. (2007) Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo.
    J. Allergy Clin. Immunol.
     120, 293-299.

    Grun, C., Berger, S., Matthes, D., Mueller, M.J. (2007) Early accumulation of non-enzymatically synthesized oxylipins in Arabidopsis thaliana after infection with Pseudomonas syringae.
    Funct. Plant Biology
    34, 1-7.

    Berger, S., Benediktyova,  Z., Matous, K., Bonfig,  K., Mueller,  M.J., Nedbal,  L., Roitsch, T. (2007) Visualization of dynamics of plant-pathogen interaction by novel combination of chlorophyll fluorescence imaging and statistical analysis: differential effects of virulent and avirulent strains of P. syringae and of oxylipins on A. thaliana.
    J. Exp. Bot.
    58, 797-806.

    Karg, K., Dirsch, V., Vollmar, A.M., Cracowski, J.-L., Laporte, F., Mueller, M.J. (2007) Biologically active oxidized lipids (phytoprostanes) in the plant diet and parenteral nutrition.
    Free Rad. Res. 41, 25-37.


    2006

    Sattler, S.E., Mene-Saffrane, L., Farmer, E.E., Krischke, M., Mueller, M.J., DellaPenna, D. (2006) Non-enzymatic lipid peroxidation reprograms gene expression and activates defense markers in tocopherol deficient mutants.
    Plant Cell
    18, 3706-3720.

    Deeken, R., Engelmann, J.C., Efetova, M., Czirjak, T., Müller, T., Kaiser, W.M., Tietz, O., Krischke, M., Mueller, M.J., Palme, K., Dandekar, T., Hedrich, R. (2006) An Integrated View of Gene Expression and Solute Profiles of Arabidopsis Tumors: A Genome-Wide Approach.
    Plant Cell
    18, 3617-3634.

    Raake, I., Mueller, M.J., Berger, S. (2006) Defects in allene oxide synthase and OPDA reductase alter the resistance to Pseudomonas syringae and Botrytis cinerea.
    J. Phytopath.
    154, 740-744.

    Raake, I., v. Rad, U., Mueller, M.J., Berger, S. (2006) Yeast increases resistance in Arabidopsis against Pseudomonas syringae and Botrytis cinerea by plant-dependent as well as plant independent mechanism.
    Mol. Plant Microbe Interaction
    19, 1138-1146.

    Mueller, M.J., Laurent, M.-S., Grun, C., Karg, K., Farmer, E.E. (2006) Oxylipin analysis.
    Plant J.
    45, 472-489.


    2005

    De Vos, M., Van Oosten, V.R., Van Poecke, R.M.P., Van Pelt, J.A., Pozo, M.J., Mueller, M.J., Buchala, A.J., Métraux, J.-P., Van Loon, L.C., Dicke, M., Pieterse, C.M.J.  (2005) Signal signature and transcriptome changes of Arabidopsis during pathogen and insect attack.
    Mol. Plant-Microbe Interact.
    18, 923-937.

    Traidl-Hoffmann, C., Mariani, V., Hochrein, H., Karg, K., Wagner, H., Ring, J., Mueller, M.J., Jakob, T., Behrendt, H. (2005) Pollen associated phytoprostanes inhibit dendritic cell IL-12 production and augment Th2 cell polarization.
    J. Exp. Med.
    201, 627-636. (Highlight article).
    Comments: Pollen polarize dentritic cells (2005) J.Exp.Med. 201: 486; Pollen power (2005) Nat. Med. 11: 259; Allergic oil (2005), Nat. Immun. 6, 371.

    Loeffler, C., Berger, S., Durand, T., Bringmann, G., Dreyer, M., von Rad, U., Durner, J., Mueller, M.J. (2005) B1-phytoprostanes trigger plant defence and detoxification responses.
    Plant Physiol. 137, 328-340.

    Iqbal, M., Evans, P., Lledó, A., Verdaguer, X., Pericás, M.A., Riera, A., Loeffler, C., Sinha, A.K., Mueller, M.J. (2005) Total synthesis and biological activity of 13,14-dehydro-12-oxo-phytodienoic acids (deoxy-J1-phytoprostanes).
    Chem. Bio. Chem.
    6, 276-280.

    von Rad, U., Mueller, M.J., Durner, J. (2005) Evaluation of natural and synthetic stimulants of plant immunity by microarray technology.
    New Phytologist 165, 191-202.


    2004

    Mueller, M.J. (2004) Phytoprostanes: bioactive isoprostanes from plants.
    Prostaglandins, Leukot. Essential Fatty Acids 71, 39-40.

    Stuhlfelder, C., Mueller, M.J., Warzecha, H., (2004) Cloning and expression of a tomato cDNA encoding a methyl jasmonate cleeaving esterase.
    Eur. J. Biochem.
    271, 2976-2983.

    Mueller, M.J. (2004) Archetype signals in plants: the phytoprostanes.
    Curr. Opin. Plant Biol.
    7, 441-448.

    Zeier, J., Pink, B., Mueller, M.J., Berger, S., (2004) Light conditions influence specific defense responses in incompatible plant-pathogen interactions: uncoupling systemic resistance from salicylic acid and PR-1 accumulation.
    Planta 219, 673-683.

    Huang, X., Stettmaier, K., Michel, C., Hutzler, P., Mueller, M.J., Durner, J. (2004) Nitriooxide is induced by wounding and influences jasmonic acid signaling in Arabidopsis thaliana.
    Planta
    218, 938-946.

    Thoma, I., Krischke, M., Loeffler, C., Mueller, M.J. (2004) The isoprostanoid pathway in plants.
    Chem. Phys. Lipids 128, 135-148.


    2003

    Loeffler, C., Thoma, I., Krischke, M., Mueller, M.J. (2003) The dinor isoproatane pathway in plants.
    Adv. Exp. Med. Biol.
    525, 217-220.

    Thoma, I., Loeffler, C., Sinha, A., Gupta, M., Krischke, M., Steffan, B., Roitsch, T., Mueller, M.J.  (2003) Cyclopentenone isoprostanes induced by reactive oxygen species trigger defense gene activation and phytoalexin accumulation in plants (Highlight article),
    Plant J.
    34, 363-375.

    Krischke, M., Loeffler, C., Mueller, M.J., (2003) Archetypische Prostanoide in Pflanzen.
    Bioforum
    3, 2-4.

    Spoel, S.H., Koornneef, A., Claessens, S.M.C., Korzelius, J.P., van Pelt, J.A., Mueller, M.J., Buchala, A.J., Metraux, J.-P., Brown, R., Kazan, K., van Loon, L.C., Dong, X., Pieterse, (2003) NPR1 modulates cross-talk between salicylate- and jasmonate-dependent plant defense pathways through a novel function in the cytosol.
    Plant Cell
    15, 760-770.

    Krischke, M., Loffler, C., Mueller, M.J. (2003) Biosynthesis of 13,14-dehydro-12-oxo-phytodienoic acid and related cyclopentenones via the phytoprostane D1 pathway.
    Phytochemistry
    62, 351-358.


    2002

    Stuhlfelder, C., Lottspeich, F., Mueller, M.J. (2002) Purification and partial amino acid sequences of an esterase from tomato.
    Phytochemistry 60, 233-240.

    Mueller, M.J. (2002) Prostaglandin-like octadecanoids in plants: Biosynthesis, molecular signalling and response to environment.
    Lipid biotechnology, Marcel Dekker, New York, (eds. Kuo Gardner), 203-229.


    2000

    Pieterse, C.M.J., van Pelt, J.A., Ton, J., Parchmann, S., Mueller, M.J., Buchala, A.J., Metraux, J.-P., van Loon, L.C. (2000) Rhizobacteria-mediated induced systemic resistance (IRS) in Arabidopsis requires sensitivity to jasmonate and ethylene but is not accompanied by an increase in their production.
    Physiol. Mol. Plant Pathol. 57, 123-134.

    Imbusch, R., Mueller, M.J. (2000) Analysis of oxidative stress and wound-inducible dinor isoprostanes F1 (phytoprostanes F1) in plants.
    Plant Physiol. 124, 1293-1304.

    Imbusch, R., Mueller, M.J. (2000) Dinor isoprostanes F1 formation in higher plants: High concentrations in plant drugs and flower pollen.
    Free Rad. Biol. Med. 28, 720-726.


    1999

    O'Sullivan, S., Mueller, M.J., Dahlén, S.-E., Kumlin, M. (1999) Analyses of prostaglandin D2 metabolites in urine: comparison between enzyme immunoassay and negative ion chemical ionisation gas chromatography - mass spectrometry.
    Prostaglandins Other Lipid Med. 57, 149-165.

    Menke, F.L.H., Parchmann, S., Mueller, M.J., Kijne, J.W., Memelink, J. (1999) Involvement of the octadecanoid pathway and protein phosphorylation in fungal-elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in Catharanthus roseus.
    Plant Physiol. 199, 1289-1296.


    1998

    Mueller, M.J. (1998) Redically novel prostaglandins in animals and plants: The isoprostanes.
    Chemistry & Biology 5, 323-333.

    Parchmann, S., Mueller, M.J. (1998) Evidence for the formation of dinor isoprostanes E1 from a-linolenic acid in plants.
    J. Biol. Chem., 273, 32650-32655.

    Krischer, S.M., Eisenmann, M., Mueller, M.J. (1998) Transport of arachidonic acid across the neutrophil plasma membrane via a protein-facilitated mechanism.
    Biochemistry, 37, 12884-12891.

    Mueller, M.J., Blomster Andberg, M., Haeggström, J.Z. (1998) Analysis of the molecular mechanism of substrate-mediated inactivation of leukotriene A4 hydrolase.
    J. Biol. Chem. 273, 11570-11575.


    1997

    Parchmann, S., Gundlach, H., Mueller, M.J. (1997) Inducation of 12-oxo-phytodienoic acid in wounded plants and elicited plant cell cultures.
    Plant Physiol. 115, 1057-1064.

    Mueller, M.J. (1997) Enzymes involved in jasmonic acid biosynthesis.
    Physiol. Plant.
    100, 653-663.

    Krischer, S.M., Eisenmann, M., Bock, A., Mueller, M.J. (1997) Protein-facilitated export of arachidonic acid from pig neutrophils.
    J. Biol. Chem.
    272, 10601-10607.


    1996

    Wetterholm, A., Mueller, M.J., Blomster, M., Samuelsson, B., Haeggström, J.Z. (1996) Studies on the active site of leukotriene A4 hydrolase.
    Adv. Exp. Med. Biol. 407, 1-7.

    Mueller, M.J., Blomster Andberg, M., Samuelson, B., Haeggström, J.Z. (1996) Leukotriene A4 hydrolase, mutation of tyrosine 378 allows conversion of leukotriene A4 into an isomer of leukotriene B4.
    J. Biol. Chem. 271, 24345-24348.

    Mueller, M.J., Blomster, M., Oppermann, Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1996) Leukotriene A4 hydrolase: Dissociation of catalysis and mechanism-based inactivation by mutation of tyrosine-378.
    Proc. Natl. Acad. Sci. USA
    93, 5931-5935.


    1995

    Mueller, M.J., Wetterholm, A., Blomster, M., Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1995) Leukotriene A4 hydrolase: Mapping of a heneicosapeptide involved in mechanism-based inactivation.
    Proc. Natl. Acad. Sci. USA
    92, 8383-8387.

    Mueller, M.J., Wetterholm, A., Blomster, M., Jörnvall, H., Samuelsson, B., Haeggström, J.Z. (1995) Leukotriene A4 hydrolase: Evidence for a catalytic role of tyrosine-383 in the peptidase reaction.
    Eur. J. Biochem.
    231, 528-534.

    Mueller, M.J. (1995) Der Leukotriensignalweg - ein vielversprechender Ansatzpunkt für Inhibitoren in der Therapie entzündlicher Erkrankungen.
    Pharmazie in unserer Zeit
    24 (5), 264-272.

    Mueller, M.J., Samuelsson, B., Haeggström, J.Z. (1995) Chemical Modification of Leukotriene A4 hydrolase: Essential Arginyl and Tyrosyl Residues at the active site.
    Biochemistry
    34, 3536-3543.

    Blechert, S., Brodschelm, W., Hölder, S., Kammerer, L., Kutchan, T.M., Mueller, M.J., Xia, Z. -Q., Zenk, M.H. (1995) The octadecanoic pathway: Signal molecules for the regulation of secondary pathways.
    Proc. Natl. Acad. Sci. USA
    92, 4099-4105.


    1994

    Mueller, M.J., Brodschelm, W. (1994) Quantification of Jasmonic Acid by Capillary Gas Chromatography-Negative Chemical Ionization-Mass Spectrometry.
    Anal. Biochem.
    218, 425-435.


    1993

    Mueller, M.J., Brodschelm, W., Spannagl, E., Zenk, M.H. (1993) Signaling in the elicitation process is mediated through the octadecanoid pathway leading to jasmonic acid.
    Proc. Natl. Acad. Sci. USA 90, 7490-7494.

    Mueller, M.J., Zenk, M. H. (1993) The Biosynthesis of the Cularine Alkaloids.
    Liebigs Ann. Chem. 557-563.

    Mueller, M.J., Zenk, M.H. (1993) Early Precursors in the Biosynthesis of Cularine-Type Benzylisoquinoline Alkaloids.
    J. Chem. Soc., Chem. Comm.
    1, 73-75.


    1992

    Mueller, M.J., Zenk, M.H. (1992) The Norcoclaurine Pathway is operative in Berberine Biosynthesis in Coptis japonica.
    Planta Med.
    58, 485-574.

    Gundlach, H., Müller, M.J., Kutchan, T.M., Zenk, M.H. (1992) Jasmonic acid is a signal transducer in elicitor-induced plant cell cultures.
    Proc. Natl. Acad. Sci. USA 89, 2389-2393.

    Mueller, M.J. (1992) Die Biosynthese der Benzylisochinolinalkaloide vom Cularin-Typ sowie Untersuchungen zum Elicitierungsgeschehen in pflanzlichen Zellkulturen. Dissertation, Ludwigs-Maximilian-Universität München.

     

    Kontakt

    Lehrstuhl für Pharmazeutische Biologie
    Julius-von-Sachs-Platz 2
    97082 Würzburg

    Tel.: +49 931 31-86161
    Fax: +49 931 31-86158
    E-Mail

    Suche Ansprechpartner

    Julius-von-Sachs-Platz 2 Hubland Süd, Geb. B1 Hubland Nord, Geb. 32 Fabrikschleichach Hubland Süd, Geb. B2 Hubland Süd, Geb. B3